Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala

Converging evidence suggests a role of serotonin (5-hydroxytryptamine, 5-HT) and tryptophan hydroxylase 2 (TPH2), the rate-limiting enzyme of 5-HT synthesis in the brain, in modulating long-term, neurobiological effects of early-life adversity. Here, we aimed at further elucidating the molecular mec...

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Udgivet i:Front Neurosci
Main Authors: Weidner, Magdalena T., Lardenoije, Roy, Eijssen, Lars, Mogavero, Floriana, De Groodt, Lilian P. M. T., Popp, Sandy, Palme, Rupert, Förstner, Konrad U., Strekalova, Tatyana, Steinbusch, Harry W. M., Schmitt-Böhrer, Angelika G., Glennon, Jeffrey C., Waider, Jonas, van den Hove, Daniel L. A., Lesch, Klaus-Peter
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524554/
https://ncbi.nlm.nih.gov/pubmed/31133792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00460
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