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Nanoformulation of Talazoparib Delays Tumor Progression and Ascites Formation in a Late Stage Cancer Model

Talazoparib, a potent PARP inhibitor, induces synthetic lethality in BRCA-deficient cancers making it an attractive candidate for ovarian cancer treatment. However, its potency lends itself to side effects associated more closely with traditional chemotherapeutics than other clinically approved PARP...

詳細記述

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書誌詳細
出版年:Front Oncol
主要な著者: Baldwin, Paige, Ohman, Anders W., Medina, Jamie E., McCarthy, Eric T., Dinulescu, Daniela M., Sridhar, Srinivas
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524318/
https://ncbi.nlm.nih.gov/pubmed/31134152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00353
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