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In vitro analysis of PARP inhibitor nanoformulations
PARP-l is a DNA repair protein that plays a role in a number of repair pathways and also helps in transcriptional regulation; thus PARP inhibitors (PARPi), such as olaparib and BMN-673, act by inhibiting DNA damage repair. This leads to an accumulation of deleterious mutations leading to genetic ins...
Sparad:
| I publikationen: | Int J Nanomedicine |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Dove Medical Press
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5863639/ https://ncbi.nlm.nih.gov/pubmed/29593397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S124992 |
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