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In vitro analysis of PARP inhibitor nanoformulations

PARP-l is a DNA repair protein that plays a role in a number of repair pathways and also helps in transcriptional regulation; thus PARP inhibitors (PARPi), such as olaparib and BMN-673, act by inhibiting DNA damage repair. This leads to an accumulation of deleterious mutations leading to genetic ins...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Baldwin, Paige, Tangutoori, Shifalika, Sridhar, Srinivas
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863639/
https://ncbi.nlm.nih.gov/pubmed/29593397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S124992
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