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Structural Stabilization of Human Transthyretin by Centella asiatica (L.) Urban Extract: Implications for TTR Amyloidosis

Transthyretin is responsible for a series of highly progressive, degenerative, debilitating, and incurable protein misfolding disorders known as transthyretin (TTR) amyloidosis. Since dissociation of the homotetrameric protein to its monomers is crucial in its amyloidogenesis, stabilizing the native...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biomolecules
Päätekijät: Eze, Fredrick Nwude, Leelawatwattana, Ladda, Prapunpoj, Porntip
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523946/
https://ncbi.nlm.nih.gov/pubmed/30934952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9040128
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