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Comparative RNAi Screens in Isogenic Human Stem Cells Reveal SMARCA4 as a Differential Regulator

Large-scale RNAi screens are a powerful approach to identify functions of genes in a cell-type-specific manner. For model organisms, genetically identical (isogenic) cells from different cell types are readily available, making comparative studies meaningful. However, large-scale screens in isogenic...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Güneş, Ceren, Paszkowski-Rogacz, Maciej, Rahmig, Susann, Khattak, Shahryar, Camgöz, Aylin, Wermke, Martin, Dahl, Andreas, Bornhäuser, Martin, Waskow, Claudia, Buchholz, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523874/
https://ncbi.nlm.nih.gov/pubmed/31031192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.03.012
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