Comparing the Utility of Mitochondrial and Nuclear DNA to Adjust for Genetic Ancestry in Association Studies

Mitochondrial genome-wide association studies identify mitochondrial single nucleotide polymorphisms (mtSNPs) that associate with disease or disease-related phenotypes. Most mitochondrial and nuclear genome-wide association studies adjust for genetic ancestry by including principal components derive...

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Udgivet i:Cells
Main Authors: Miller, Brendan, Arpawong, Thalida E., Jiao, Henry, Kim, Su-Jeong, Yen, Kelvin, Mehta, Hemal H., Wan, Junxiang, Carpten, John C., Cohen, Pinchas
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523867/
https://ncbi.nlm.nih.gov/pubmed/30987182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8040306
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