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Amphiphilic Peptides for Efficient siRNA Delivery

A number of amphiphilic cyclic peptides—[FR](4), [WR](5), and [WK](5)—containing hydrophobic and positively-charged amino acids were synthesized by Fmoc/tBu solid-phase peptide methods and evaluated for their efficiency in intracellular delivery of siRNA to triple-negative breast cancer cell lines,...

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Détails bibliographiques
Publié dans:Polymers (Basel)
Auteurs principaux: Mozaffari, Saghar, Bousoik, Emira, Amirrad, Farideh, Lamboy, Robert, Coyle, Melissa, Hall, Ryley, Alasmari, Abdulaziz, Mahdipoor, Parvin, Parang, Keykavous, Montazeri Aliabadi, Hamidreza
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523661/
https://ncbi.nlm.nih.gov/pubmed/30999603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym11040703
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