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Tumor-targeted delivery of siRNA using fatty acyl-CGKRK peptide conjugates

Tumor-targeted carriers provide efficient delivery of chemotherapeutic agents to tumor tissue. CGKRK is one of the well-known tumor targeting peptides with significant specificity for angiogenic blood vessels and tumor cells. Here, we designed fatty acyl conjugated CGKRK peptides, based on the hypot...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sharma, Meenakshi, El-Sayed, Naglaa Salem, Do, Hung, Parang, Keykavous, Tiwari, Rakesh Kumar, Aliabadi, Hamidreza Montazeri
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522445/
https://ncbi.nlm.nih.gov/pubmed/28733622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06381-y
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