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Synthesis and Antiproliferative Activities of Conjugates of Paclitaxel and Camptothecin with a Cyclic Cell-Penetrating Peptide
Cell-penetrating peptide [WR](5) has been previously shown to be an efficient molecular transporter for various hydrophilic and hydrophobic molecules. The peptide was synthesized using Fmoc/tBu solid-phase chemistry, and one arginine was replaced with one lysine to enable the conjugation with the an...
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| Published in: | Molecules |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6480016/ https://ncbi.nlm.nih.gov/pubmed/30978971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24071427 |
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