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Cellular and Animal Models of Striated Muscle Laminopathies

The lamin A/C (LMNA) gene codes for nuclear intermediate filaments constitutive of the nuclear lamina. LMNA has 12 exons and alternative splicing of exon 10 results in two major isoforms—lamins A and C. Mutations found throughout the LMNA gene cause a group of diseases collectively known as laminopa...

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Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Nicolas, Hannah A., Akimenko, Marie-Andrée, Tesson, Frédérique
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523539/
https://ncbi.nlm.nih.gov/pubmed/30934932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8040291
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