Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5

Human retinal organoids from induced pluripotent stem cells (hiPSCs) can be used to confirm the localization of proteins in retinal cell types and to test transduction and expression patterns of gene therapy vectors. Here, we compared the onset of CRB protein expression in human fetal retina with hu...

Full description

Saved in:
Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Quinn, Peter M., Buck, Thilo M., Mulder, Aat A., Ohonin, Charlotte, Alves, C. Henrique, Vos, Rogier M., Bialecka, Monika, van Herwaarden, Tessa, van Dijk, Elon H.C., Talib, Mays, Freund, Christian, Mikkers, Harald M.M., Hoeben, Rob C., Goumans, Marie-José, Boon, Camiel J.F., Koster, Abraham J., Chuva de Sousa Lopes, Susana M., Jost, Carolina R., Wijnholds, Jan
Format: Artigo
Language:Inglês
Published: Elsevier 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522954/
https://ncbi.nlm.nih.gov/pubmed/30956116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.03.002
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items