Molecular modeling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime, 4-PA, 2-PAM, and obidoxime with VX-inhibited human acetylcholinesterase: a near attack conformation approach

7-methoxytacrine-4-pyridinealdoxime (7-MEOTA-4-PA, named hybrid 5C) is a compound formerly synthesized and evaluated in vitro, together with 4-pyridine aldoxime (4-PA) and commercial reactivators of acetylcholinesterase (AChE). This compound was designed with the purpose of being a prophylactic reac...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: da Silva, Jorge Alberto Valle, Nepovimova, Eugenie, Ramalho, Teodorico Castro, Kuca, Kamil, Celmar Costa França, Tanos
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522925/
https://ncbi.nlm.nih.gov/pubmed/31074292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1609953
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados