miR-216a exacerbates TGF-β-induced myofibroblast transdifferentiation via PTEN/AKT signaling

Myofibroblast transdifferentiation is an important feature of cardiac fibrosis. Previous studies have indicated that microRNA-216a (miR-216a) is upregulated in response to transforming growth factor-β (TGF-β) in kidney cells and can activate Smad3; however, its role in myofibroblast transdifferentia...

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Detaylı Bibliyografya
Yayımlandı:Mol Med Rep
Asıl Yazarlar: Qu, Chuan, Liu, Xin, Ye, Tianxin, Wang, Linglin, Liu, Steven, Zhou, Xingyu, Wu, Gang, Lin, Jian, Shi, Shaobo, Yang, Bo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2019
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522872/
https://ncbi.nlm.nih.gov/pubmed/31059054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10200
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