A lasered mouse model of retinal degeneration displays progressive outer retinal pathology providing insights into early geographic atrophy

Early stages of geographic atrophy (GA) age-related macular degeneration is characterised by the demise of photoreceptors, which precedes the loss of underlying retinal pigment epithelial (RPE) cells. Sight-loss due to GA has no effective treatment; reflecting both the complexity of the disease and...

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Vydáno v:Sci Rep
Hlavní autoři: Ibbett, Paul, Goverdhan, Srinivas V., Pipi, Elena, Chouhan, Joe K., Keeling, Eloise, Angus, Elizabeth M., Scott, Jenny A., Gatherer, Maureen, Page, Anton, Teeling, Jessica L., Lotery, Andrew J., Arjuna Ratnayaka, J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522499/
https://ncbi.nlm.nih.gov/pubmed/31097765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43906-z
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