Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues

Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) have the ability of differentiating into functional cardiomyocytes (CMs) for cell replacement therapy, tissue engineering, drug discovery and toxicity screening. From a scale-free, co-expression network analysis of transcr...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chow, Maggie Zi-Ying, Sadrian, Stephanie N., Keung, Wendy, Geng, Lin, Ren, Lihuan, Kong, Chi-Wing, Wong, Andy On-Tik, Hulot, Jean-Sebastien, Chen, Christopher S., Costa, Kevin D., Hajjar, Roger J., Li, Ronald A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522495/
https://ncbi.nlm.nih.gov/pubmed/31097748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42953-w
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