MALAT1 regulates the transcriptional and translational levels of proto-oncogene RUNX2 in colorectal cancer metastasis

Ectopic expression of lncRNA-MALAT1 has been discovered in recurrent colorectal cancer (CRC) and metastatic sites in postsurgical patients, however, its biological mechanism remained unelucidated. Our study first revealed the novel roles of MALAT1 in promoting CRC metastasis through two mechanisms:...

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Udgivet i:Cell Death Dis
Main Authors: Ji, Qing, Cai, Guoxiang, Liu, Xuan, Zhang, Yi, Wang, Yan, Zhou, Lihong, Sui, Hua, Li, Qi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522477/
https://ncbi.nlm.nih.gov/pubmed/31097689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1598-x
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