JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway

BACKGROUND: Our previous work demonstrated that lncRNA-MALAT1 was overexpressed in recurrent colorectal cancer (CRC) and metastatic sites in post-surgical patients. However, the upstream regulatory mechanism of MALAT1 is not well-defined. Histone demethylase JMJD2C holds great potential of epigeneti...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wu, Xinnan, Li, Ruixiao, Song, Qing, Zhang, Chengcheng, Jia, Ru, Han, Zhifen, Zhou, Lihong, Sui, Hua, Liu, Xuan, Zhu, Huirong, Yang, Liu, Wang, Yan, Ji, Qing, Li, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819649/
https://ncbi.nlm.nih.gov/pubmed/31665047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1439-x
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