JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway

BACKGROUND: Our previous work demonstrated that lncRNA-MALAT1 was overexpressed in recurrent colorectal cancer (CRC) and metastatic sites in post-surgical patients. However, the upstream regulatory mechanism of MALAT1 is not well-defined. Histone demethylase JMJD2C holds great potential of epigeneti...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Wu, Xinnan, Li, Ruixiao, Song, Qing, Zhang, Chengcheng, Jia, Ru, Han, Zhifen, Zhou, Lihong, Sui, Hua, Liu, Xuan, Zhu, Huirong, Yang, Liu, Wang, Yan, Ji, Qing, Li, Qi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819649/
https://ncbi.nlm.nih.gov/pubmed/31665047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1439-x
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires