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Molecular imaging of deoxycytidine kinase activity using deoxycytidine-enhanced CEST MRI

Deoxycytidine kinase (DCK) is a key enzyme for the activation of a broad spectrum of nucleoside-based chemotherapy drugs (e.g., gemcitabine); low DCK activity is one of the most important causes of cancer drug-resistance. Noninvasive imaging methods that can quantify DCK activity are invaluable for...

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Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: Han, Zheng, Li, Yuguo, Zhang, Jia, Liu, Jing, Chen, Chuheng, van Zijl, Peter C., Liu, Guanshu
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522309/
https://ncbi.nlm.nih.gov/pubmed/30940660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3565
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