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Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T cells in Trastuzumab-treated Patients using Imaging Mass Cytometry
PURPOSE: Imaging Mass Cytometry (IMC) uses metal-conjugated antibodies to provide multidimensional, objective measurement of protein targets. We used this high-throughput platform to perform an 18-plex assessment of HER2 ICD/ECD, cytotoxic T cell infiltration and other structural and signaling prote...
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| Publicado en: | Clin Cancer Res |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522272/ https://ncbi.nlm.nih.gov/pubmed/30796036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2599 |
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