Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T cells in Trastuzumab-treated Patients using Imaging Mass Cytometry

PURPOSE: Imaging Mass Cytometry (IMC) uses metal-conjugated antibodies to provide multidimensional, objective measurement of protein targets. We used this high-throughput platform to perform an 18-plex assessment of HER2 ICD/ECD, cytotoxic T cell infiltration and other structural and signaling prote...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Clin Cancer Res
Hlavní autoři: Carvajal-Hausdorf, Daniel E., Patsenker, Jonathan, Stanton, Kelly, Espindola, Franz Villarroel, Esch, Amanda, Montgomery, Ruth R., Psyrri, Amanda, Kalogeras, Konstantine T., Kotoula, Vasiliki, Fountzilas, George, Schalper, Kurt A., Kluger, Yuval, Rimm, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522272/
https://ncbi.nlm.nih.gov/pubmed/30796036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2599
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky