Usefulness of Canakinumab to Improve Exercise Capacity in Patients With Long-Term Systolic Heart Failure and Elevated C-Reactive Protein

Interleukin-1β (IL-1 β) is a cytokine involved in atherothrombosis and is known to depress cardiac function. We hypothesized that blocking IL-1 β in patients with symptomatic systolic heart failure (HF) would improve their cardiorespiratory fitness. The purpose of the study was to measure changes in...

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Dettagli Bibliografici
Pubblicato in:Am J Cardiol
Autori principali: Trankle, Cory R., Canada, Justin M., Cei, Laura, Abouzaki, Nayef, Oddi-Erdle, Claudia, Kadariya, Dinesh, Christopher, Sanah, Viscusi, Michele, Buono, Marco Del, Kontos, Michael C., Arena, Ross, Tassell, Benjamin Van, Abbate, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522244/
https://ncbi.nlm.nih.gov/pubmed/30244844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjcard.2018.07.002
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