Chargement en cours...

Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy

The transcription factor Oct1/Pou2f1 promotes poised gene expression states, mitotic stability, glycolytic metabolism and other characteristics of stem cell potency. To determine the effect of Oct1 loss on stem cell maintenance and malignancy, we deleted Oct1 in two different mouse gut stem cell com...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Vázquez-Arreguín, Karina, Bensard, Claire, Schell, John C., Swanson, Eric, Chen, Xinjian, Rutter, Jared, Tantin, Dean
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522070/
https://ncbi.nlm.nih.gov/pubmed/31059499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007687
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!