Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy

The transcription factor Oct1/Pou2f1 promotes poised gene expression states, mitotic stability, glycolytic metabolism and other characteristics of stem cell potency. To determine the effect of Oct1 loss on stem cell maintenance and malignancy, we deleted Oct1 in two different mouse gut stem cell com...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Vázquez-Arreguín, Karina, Bensard, Claire, Schell, John C., Swanson, Eric, Chen, Xinjian, Rutter, Jared, Tantin, Dean
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522070/
https://ncbi.nlm.nih.gov/pubmed/31059499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007687
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller