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Does MHC heterozygosity influence microbiota form and function?

MHC molecules are essential for the adaptive immune response, and they are the most polymorphic genetic loci in vertebrates. Extreme genetic variation at these loci is paradoxical given their central importance to host health. Classic models of MHC gene evolution center on antagonistic host-pathogen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Khan, M. A. Wadud, Stephens, W. Zac, Mohammed, Ahmed Dawood, Round, June Louise, Kubinak, Jason Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522005/
https://ncbi.nlm.nih.gov/pubmed/31095603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215946
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