MyD88 signaling in T cells directs IgA-mediated control of the microbiota to promote health

Altered commensal communities are associated with human disease. IgA mediates intestinal homeostasis and regulates microbiota composition. Intestinal IgA is produced at high levels as a result of T follicular helper cell (T(FH)) and B cell interactions in germinal centers. However, the pathways dire...

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Detaylı Bibliyografya
Yayımlandı:Cell Host Microbe
Asıl Yazarlar: Kubinak, Jason L., Petersen, Charisse, Stephens, W. Zac, Soto, Ray, Bake, Erin, O’Connell, Ryan M., Round, June L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451207/
https://ncbi.nlm.nih.gov/pubmed/25620548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.12.009
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