MyD88 signaling in T cells directs IgA-mediated control of the microbiota to promote health

Altered commensal communities are associated with human disease. IgA mediates intestinal homeostasis and regulates microbiota composition. Intestinal IgA is produced at high levels as a result of T follicular helper cell (T(FH)) and B cell interactions in germinal centers. However, the pathways dire...

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Библиографические подробности
Опубликовано в: :Cell Host Microbe
Главные авторы: Kubinak, Jason L., Petersen, Charisse, Stephens, W. Zac, Soto, Ray, Bake, Erin, O’Connell, Ryan M., Round, June L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451207/
https://ncbi.nlm.nih.gov/pubmed/25620548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.12.009
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