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Proliferative tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells

Selective differentiation of naïve T lymphocytes into multipotent T cells is of great interest clinically for the generation of cell-based cancer immunotherapies. Cellular differentiation depends crucially on division state and time. Here we adapt a dye-dilution assay for tracking cell proliferative...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Biotechnol
Hauptverfasser: Good, Zinaida, Borges, Luciene, Gonzalez, Nora Vivanco, Sahaf, Bita, Samusik, Nikolay, Tibshirani, Robert, Nolan, Garry P., Bendall, Sean C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521980/
https://ncbi.nlm.nih.gov/pubmed/30742126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0033-2
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