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Presenilin regulates retinotectal synapse formation through EphB2 receptor processing

As the catalytic component of γ-secretase, presenilin (PS) has long been studied in the context of Alzheimer’s disease through cleaving the amyloid precursor protein. PS/γ-secretase, however, also cleaves a multitude of single-pass transmembrane proteins that are important during development, includ...

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Detalhes bibliográficos
Publicado no:Dev Neurobiol
Main Authors: Liu, Zhenyu, Thakar, Amit, Santoro, Stephen W., Pratt, Kara G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521963/
https://ncbi.nlm.nih.gov/pubmed/30246932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22638
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