Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma

Glioblastoma harbors frequent alterations in receptor tyrosine kinases, phosphatidylinositol-3 kinase (PI3K) and phosphatase and tensin homolog (PTEN) that dysregulate phospholipid signaling driven tumor proliferation and therapeutic resistance. Myristoylated alanine-rich C-kinase substrate (MARCKS)...

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Gepubliceerd in:Int J Oncol
Hoofdauteurs: Eustace, Nicholas J., Anderson, Joshua C., Langford, Catherine P., Trummell, Hoa Q., Hicks, Patricia H., Jarboe, John S., Mobley, James A., Hjelmeland, Anita B., Hackney, James R., Pedersen, Rune T., Cosby, Kadia, Gillespie, G. Yancey, Bonner, James A., Willey, Christopher D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521926/
https://ncbi.nlm.nih.gov/pubmed/30942445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4766
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