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The ER Membrane Protein Complex Promotes Biogenesis of Dengue and Zika Virus Non-structural Multi-pass Transmembrane Proteins to Support Infection

Although flaviviruses co-opt the function of the host endoplasmic reticulum (ER) membrane protein complex (EMC) during infection, a mechanistic explanation for this observation remains unclear. Here, we show that the EMC promotes biogenesis of dengue virus (DENV) and Zika virus (ZIKV) non-structural...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Lin, David L., Inoue, Takamasa, Chen, Yu-Jie, Chang, Aaron, Tsai, Billy, Tai, Andrew W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521869/
https://ncbi.nlm.nih.gov/pubmed/31067454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.051
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