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An ER translocon for multi-pass membrane protein biogenesis
Membrane proteins with multiple transmembrane domains play critical roles in cell physiology, but little is known about the machinery coordinating their biogenesis at the endoplasmic reticulum. Here we describe a ~ 360 kDa ribosome-associated complex comprising the core Sec61 channel and five access...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7505659/ https://ncbi.nlm.nih.gov/pubmed/32820719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56889 |
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