Structure reveals mechanism of CRISPR RNA-guided nuclease recruitment and anti-CRISPR viral mimicry

Bacteria and archaea have evolved sophisticated adaptive immune systems that rely on CRISPR RNA (crRNA)-guided detection and nuclease-mediated elimination of invading nucleic acids. Here we present the cryo-EM structure of the type I-F CRISPR RNA-guided surveillance complex (Csy complex) from Pseudo...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Cell
Autores principales: Rollins, MaryClare F., Chowdhury, Saikat, Carter, Joshua, Golden, Sarah M., Miettinen, Heini M., Santiago-Frangos, Andrew, Faith, Dominick, Lawrence, C. Martin, Lander, Gabriel C., Wiedenheft, Blake
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521718/
https://ncbi.nlm.nih.gov/pubmed/30872121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.02.001
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares