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Sequestration of 9-Hydroxystearic Acid in FAHFA (Fatty Acid Esters of Hydroxy Fatty Acids) as a Protective Mechanism for Colon Carcinoma Cells to Avoid Apoptotic Cell Death

Hydroxy fatty acids are known to cause cell cycle arrest and apoptosis. The best studied of them, 9-hydroxystearic acid (9-HSA), induces apoptosis in cell lines by acting through mechanisms involving different targets. Using mass spectrometry-based lipidomic approaches, we show in this study that 9-...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Rodríguez, Juan P., Guijas, Carlos, Astudillo, Alma M., Rubio, Julio M., Balboa, María A., Balsinde, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521239/
https://ncbi.nlm.nih.gov/pubmed/31013768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040524
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