Capsaicin Analogues Derived from n-3 Polyunsaturated Fatty Acids (PUFAs) Reduce Inflammatory Activity of Macrophages and Stimulate Insulin Secretion by β-Cells In Vitro

In this study, two capsaicin analogues, N-eicosapentaenoyl vanillylamine (EPVA) and N-docosahexaenoyl vanillylamine (DHVA), were enzymatically synthesized from their corresponding n-3 long chain polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both dietary rele...

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Veröffentlicht in:Nutrients
Hauptverfasser: Cione, Erika, Plastina, Pierluigi, Pingitore, Attilio, Perri, Mariarita, Caroleo, Maria Cristina, Fazio, Alessia, Witkamp, Renger, Meijerink, Jocelijn
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520993/
https://ncbi.nlm.nih.gov/pubmed/31022842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11040915
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