Dasatinib Treatment Increases Sensitivity to c-Met Inhibition in Triple-Negative Breast Cancer Cells

In pre-clinical studies, triple-negative breast cancer (TNBC) cells have demonstrated sensitivity to the multi-targeted kinase inhibitor dasatinib; however, clinical trials with single-agent dasatinib showed limited efficacy in unselected populations of breast cancer, including TNBC. To study potent...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Gaule, Patricia, Mukherjee, Nupur, Corkery, Brendan, Eustace, Alex J., Gately, Kathy, Roche, Sandra, O’Connor, Robert, O’Byrne, Kenneth J., Walsh, Naomi, Duffy, Michael J., Crown, John, O’Donovan, Norma
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520724/
https://ncbi.nlm.nih.gov/pubmed/30999598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040548
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