Acute Hypoxia Profile is a Stronger Prognostic Factor than Chronic Hypoxia in Advanced Stage Head and Neck Cancer Patients

Hypoxic head and neck tumors respond poorly to radiotherapy and can be identified using gene expression profiles. However, it is unknown whether treatment outcome is driven by acute or chronic hypoxia. Gene expression data of 398 head and neck cancers was collected. Four clinical hypoxia profiles we...

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Pubblicato in:Cancers (Basel)
Autori principali: van der Heijden, Martijn, de Jong, Monique C., Verhagen, Caroline V. M., de Roest, Reinout H., Sanduleanu, Sebastian, Hoebers, Frank, Leemans, C. René, Brakenhoff, Ruud H., Vens, Conchita, Verheij, Marcel, van den Brekel, Michiel W. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520712/
https://ncbi.nlm.nih.gov/pubmed/31027242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040583
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