Genetic Variants as Predictive Markers for Ototoxicity and Nephrotoxicity in Patients with Locally Advanced Head and Neck Cancer Treated with Cisplatin-Containing Chemoradiotherapy (The PRONE Study)

Ototoxicity and nephrotoxicity are potentially irreversible side effects of chemoradiotherapy with cisplatin in locally advanced head and neck cancer (LAHNC) patients. Several predictive genetic variants have been described, but as yet none in LAHNC patients. The aim of this study is to investigate...

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Udgivet i:Cancers (Basel)
Main Authors: Driessen, Chantal M., Ham, Janneke C., te Loo, Maroeska, van Meerten, Esther, van Lamoen, Maurits, Hakobjan, Marina H., Takes, Robert P., van der Graaf, Winette T., Kaanders, Johannes H., Coenen, Marieke J.H., van Herpen, Carla M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520709/
https://ncbi.nlm.nih.gov/pubmed/30999660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040551
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