Intracellular Zn(2+) Signaling Facilitates Mossy Fiber Input-Induced Heterosynaptic Potentiation of Direct Cortical Inputs in Hippocampal CA3 Pyramidal Cells

Repetitive action potentials (APs) in hippocampal CA3 pyramidal cells (CA3-PCs) backpropagate to distal apical dendrites, and induce calcium and protein tyrosine kinase (PTK)-dependent downregulation of Kv1.2, resulting in long-term potentiation of direct cortical inputs and intrinsic excitability (...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Eom, Kisang, Hyun, Jung Ho, Lee, Dong-gu, Kim, Sooyun, Jeong, Hyeon-Ju, Kang, Jong-Sun, Ho, Won-Kyung, Lee, Suk-Ho
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520511/
https://ncbi.nlm.nih.gov/pubmed/30833508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2130-18.2019
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