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Aquaporin 4 inhibition alters chemokine receptor expression and T cell trafficking

Aquaporins (AQPs) are water channels that mediate a variety of biological processes. However, their role in the immune system is poorly understood. We recently reported that AQP4 is expressed by naïve and memory T cells and that AQP4 blockade with a small molecule inhibitor prolongs murine heart all...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Nicosia, Michael, Miyairi, Satoshi, Beavers, Ashley, Farr, George W., McGuirk, Paul R., Pelletier, Marc F., Valujskikh, Anna
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520372/
https://ncbi.nlm.nih.gov/pubmed/31092872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43884-2
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