Serum Concentrations of 7α-hydroxy-4-cholesten-3-one are Associated with Bile Acid Diarrhea in Patients with Crohn’s Disease

BACKGROUND & AIMS: Patients with Crohn’s disease (CD) often have bile acid diarrhea (BAD), due to bile acid malabsorption following ileal resection (IR). Bile acid malabsorption increases production of 7α-hydroxy-4-cholesten-3-one (C4), a bile acid precursor. We investigated relationships betwee...

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Vydáno v:Clin Gastroenterol Hepatol
Hlavní autoři: Battat, Robert, Duijvestein, Marjolijn, Casteele, Niels Vande, Singh, Siddharth, Dulai, Parambir S., Valasek, Mark A., Mimms, Larry, McFarland, Judson, Hester, Kelly D., Renshaw, Mark, Jain, Anjali, Sandborn, William J, Boland, Brigid S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520204/
https://ncbi.nlm.nih.gov/pubmed/30448597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2018.11.012
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