Baseline Clearance of Infliximab is Associated with Requirement for Colectomy in Patients with Acute Severe Ulcerative Colitis

BACKGROUND & AIMS: Hospitalized patients with acute severe ulcerative colitis (ASUC) often require surgery. Although the tumor necrosis factor antagonist infliximab is an effective salvage therapy to prevent colectomy in patients with ASUC, optimal dosing is unclear. Calculated infliximab cleara...

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Veröffentlicht in:Clin Gastroenterol Hepatol
Hauptverfasser: Battat, Robert, Hemperly, Amy, Truong, Stephanie, Whitmire, Natalie, Boland, Brigid S., Dulai, Parambir S, Holmer, Ariela K, Nguyen, Nghia H, Singh, Siddharth, Casteele, Niels Vande, Sandborn, William J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606215/
https://ncbi.nlm.nih.gov/pubmed/32348905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2020.03.072
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