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In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta

Here, we present a method for in-depth human plasma proteome analysis based on high-resolution isoelectric focusing HiRIEF LC-MS/MS, demonstrating high proteome coverage, reproducibility and the potential for liquid biopsy protein profiling. By integrating genomic sequence information to the MS-base...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pernemalm, Maria, Sandberg, AnnSofi, Zhu, Yafeng, Boekel, Jorrit, Tamburro, Davide, Schwenk, Jochen M, Björk, Albin, Wahren-Herlenius, Marie, Åmark, Hanna, Östenson, Claes-Göran, Westgren, Magnus, Lehtiö, Janne
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519984/
https://ncbi.nlm.nih.gov/pubmed/30958262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41608
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