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Potentials of Gene Therapy for Diabetic Retinopathy: The Use of Nucleic Acid Constructs Containing a TXNIP Promoter

Diabetic retinopathy (DR) is considered as a chronic eye disease leading to blindness. DR is associated with hyperglycemia-induced oxidative stress, chronic low-grade inflammation and premature cell death. DR affects retinal capillaries, neuroretina and the retinal pigment epithelium. Recently, the...

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Publicado en:Open Access J Ophthalmol
Main Authors: Lalit, PS, Thangal, Y, Fayi, Y, Takhellambam, SD
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519956/
https://ncbi.nlm.nih.gov/pubmed/31106306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.23880/oajo-16000147
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