TXNIP regulates mitophagy in retinal Müller cells under high-glucose conditions: implications for diabetic retinopathy

Thioredoxin-interacting protein (TXNIP) is involved in oxidative stress and apoptosis in diabetic retinopathy. However, the role of TXNIP in the removal of damaged mitochondria (MT) via mitophagy, a process of macroautophagy, remains unexplored. Here we investigate the associated cellular and molecu...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Devi, Takhellambam Swornalata, Somayajulu, Mallika, Kowluru, Renu Anjan, Singh, Lalit Pukhrambam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520711/
https://ncbi.nlm.nih.gov/pubmed/28492550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.190
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