TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy

Thioredoxin Interacting Protein (TXNIP) mediates retinal inflammation, gliosis, and apoptosis in experimental diabetes. Here, we investigate the temporal response of Muller glia to high glucose (HG) and TXNIP expression using a rat Muller cell line (rMC1) in culture. We examined if HG-induced TXNIP...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Devi, Takhellambam S., Lee, Icksoo, Hüttemann, Maik, Kumar, Ashok, Nantwi, Kwaku D., Singh, Lalit P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313582/
https://ncbi.nlm.nih.gov/pubmed/22474421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/438238
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky