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Chemopreventive efficacy of the cyclooxygenase-2 (Cox-2) inhibitor, celecoxib, is predicted by adenoma expression of Cox-2 and 15-PGDH

BACKGROUND: The APC trial showed that cyclooxygenase-2 (Cox-2) inhibitor, celecoxib, decreased adenoma development in patients at high risk for colorectal cancer. A prospectively planned analysis of the APC trial tested the hypothesis that expression of target enzymes in adenomas removed before begi...

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Wang, Jiping, Cho, Nancy L., Zauber, Ann G., Hsu, Meier, Dawson, Dawn, Srivastava, Amitabh, Mitchell-Richards, Kisha A., Markowitz, Sanford D., Bertagnolli, Monica M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519921/
https://ncbi.nlm.nih.gov/pubmed/29769213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-17-0573
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