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A system-wide network reconstruction of gene regulation and metabolism in Escherichia coli

Genome-scale metabolic models have become a fundamental tool for examining metabolic principles. However, metabolism is not solely characterized by the underlying biochemical reactions and catalyzing enzymes, but also affected by regulatory events. Since the pioneering work of Covert and co-workers...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Grimbs, Anne, Klosik, David F., Bornholdt, Stefan, Hütt, Marc-Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519848/
https://ncbi.nlm.nih.gov/pubmed/31050661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006962
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