Fiber alignment drives changes in architectural and mechanical features in collagen matrices

Aligned collagen architecture is a characteristic feature of the tumor extracellular matrix (ECM) and has been shown to facilitate cancer metastasis using 3D in vitro models. Additional features of the ECM, such as pore size and stiffness, have also been shown to influence cellular behavior and are...

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Udgivet i:PLoS One
Main Authors: Taufalele, Paul V., VanderBurgh, Jacob A., Muñoz, Adam, Zanotelli, Matthew R., Reinhart-King, Cynthia A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519824/
https://ncbi.nlm.nih.gov/pubmed/31091287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216537
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