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Substrate stiffness heterogeneities disrupt endothelial barrier integrity in a micropillar model of heterogeneous vascular stiffening

Intimal stiffening has been linked with increased vascular permeability and leukocyte transmigration, hallmarks of atherosclerosis. However, recent evidence indicates age-related intimal stiffening is not uniform but rather characterized by increased point-to-point heterogeneity in subendothelial ma...

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Detalles Bibliográficos
Publicado en:Integr Biol (Camb)
Main Authors: VanderBurgh, Jacob A., Hotchkiss, Halie, Potharazu, Archit, Taufalele, Paul V., Reinhart-King, Cynthia A.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301132/
https://ncbi.nlm.nih.gov/pubmed/30382278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ib00124c
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