Hematopoietic-Specific Deletion of Foxo1 Promotes NK Cell Specification and Proliferation

We previously reported that deletion of Foxo1, via Ncr1-iCre mice from the expression of NKp46 onward, led to enhanced natural killer (NK) cell maturation and effector function. In this model, however, the role of Foxo1 in regulating NK cell specification and early development remains exclusive. Her...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Huang, Pei, Wang, Fangjie, Yang, Yao, Lai, Wenjing, Meng, Meng, Wu, Shuting, Peng, Hongyan, Wang, Lili, Zhan, Rixing, Imani, Saber, Yu, Jianhua, Chen, Bingbo, Li, Xiaohui, Deng, Youcai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519137/
https://ncbi.nlm.nih.gov/pubmed/31139183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01016
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