Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness

Background: Mannose-binding lectin (MBL) is an innate immune protein with strong biologic plausibility for protecting against influenza virus-related sepsis and bacterial co-infection. In an autopsy cohort of 105 influenza-infected young people, carriage of the deleterious MBL gene MBL2_Gly54Asp(“B”...

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Udgivet i:Front Immunol
Main Authors: Levy, Emily R., Yip, Wai-Ki, Super, Michael, Ferdinands, Jill M., Mistry, Anushay J., Newhams, Margaret M., Zhang, Yu, Su, Helen C., McLaughlin, Gwenn E., Sapru, Anil, Loftis, Laura L., Weiss, Scott L., Hall, Mark W., Cvijanovich, Natalie, Schwarz, Adam, Tarquinio, Keiko M., Mourani, Peter M., Randolph, Adrienne G.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518443/
https://ncbi.nlm.nih.gov/pubmed/31139182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01005
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